Rebuild Ancient Protein To Reveal Ancient Eart Temperature

Researchers reconstruct proteins from ancient bacteria to measure the Earth's temperature over the ages. The scientists determined that the Earth endured a massive cooling period between 500 million and 3.5 billion years ago.

“By studying proteins encoded by these primordial genes, we are able to infer information about the environmental conditions of the early Earth,” said Eric Gaucher, Ph.D., president of scientific research at the Foundation for Applied Molecular Evolution in Gainesville and the study’s lead scientist. “Genes evolve to adapt to the environmental conditions in which an organism lives. Resurrecting these since long-extinct genes gives us the opportunity to analyze and dissect the ancient surroundings that have been recorded in the gene sequence. The genes essentially behave as dynamic fossils.”

Scientists rebuild ancient proteins to reveal primordial Earth's temperature

Engineering Approach Empower Bioinformatics

One of many approach has been design to simplified biological problem. Such as protein alignment and motif findings. A simple word to represent this approach is dry lab, instead using wet lab, that cost higher than dry lab. Science daily has said

The MIT researchers focused on a pathway in yeast that controls cells' response to a specific change in the environment. The resulting model is "the simplest model you can ever reduce these systems to," said Alexander van Oudenaarden, W.M. Keck Career Development Professor in Biomedical Engineering and Associate Professor of Physics and senior author of a paper describing the work in the Jan. 25 issue of Science.

Biological Pathway Models Simplified With Engineering Approach


Thus, this improvement will be wow to the world of bioinformatics